The total number of records retrieved from this search are 14. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1145	Herpes simplex virus	Mutant	DNA	Herpesviridae	Mutant for gamma 34.5, lacZ and alpha 47 gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice model isograft for TRAMP-C2 cell line	5.0E+6 pfu	NA	Reduction in tumor growth after repated dose of virus for 4 days	Intraneoplastically	NA	NA	NA	16278413
OV_1147	Herpes simplex virus	Mutant	DNA	Herpesviridae	Mutant for gamma 34.5, lacZ and alpha 47 gene	No	Virus strain in combination with androgen ablation therapy	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice model isograft for TRAMP-C2 cell line	5.0E+6 pfu	NA	Reduction in tumor volume as compared to castration	Subcutaneous	NA	NA	NA	16278413
OV_1840	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	virus expressing SV5-F gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mic, injected for TRAMP-C2 cell line	2.0E+7 pfu	NA	Reduction in tumor volume after 30 days	Intratumoral	Virus induce apoptosis in cancer cells	NA	NA	20172545
OV_1841	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing GFP protein	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mic, injected for TRAMP-C2 cell line	2.0E+7 pfu	NA	Reduction in tumor volume after 42 days	Intratumoral	Virus induce apoptosis in cancer cells	NA	NA	20172545
OV_4395	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and c-Myc gene	No	VSV-HIF2alpha+ VSV-sox10+ VSV-cMYC	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	60% mice survived on day 30, 20% mice survived on day 45 and last mice survived on day 60	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4396	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and GFP gene	No	VSV-HIF2alpha+ VSV-sox10+ VSV-GFP	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	All mice survived upto day 30 fter that all was dead	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4397	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing N-Ras, cytC and TYRP-1 gene	No	VSV-N-Ras+VSV-cytC+ VSV-TYRP-1	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	All mice survived upto day 10 fter that all was dead	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4398	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and c-Myc gene	No	VSV-HIF2alpha, VSV-Sox10+ VSV-cMyc+antiPD1	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	Mice survived upto day 45	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4399	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	Virus expressing HIF2alpha, Sox10 and c-Myc gene	No	VSV-HIF2alpha, VSV-Sox10+ VSV-cMyc+IgG	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	Mice survived upto day 35	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_4400	Vesicular stomatitis virus	Mutant	RNA	Rhabdoviridae	virus expressing GFP	No	VSV-GFp+anti-GFP	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL261 cell line	5.0E+6 pfu	NA	Mice survived upto day 12	Intravenous	NA	AntiPD-1 antibody enhances the IL-17 and IFN-gamma production	NA	26409567
OV_5124	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for B16-OVA (1.0E+5 cells)	3.0E+6 on day 0 and 1.0E+6 on day 2	NA	Reduction in tumor volume to 100 cubic mm compared to control 500 cubic mm after 12 days	Intratumoral	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5125	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for B16-OVA (1.0E+5 cells)	3.0E+6 on day 0 and 1.0E+6 on day 2	NA	Complete reduction in tumor volumecompared to control 500 cubic mm after 12 days	Intratumoral	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5677	Herpes simplex virus	HSV-R8306	DNA	Herpesviridae	Deletion mutant for Gamma 34.5 gene and addition of IL-4 gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL-261 (1.0E+5)	1.0E+6 pfu	NA	Increase in survival of mice up to 28 day	Intratumoral	NA	NA	NA	US7744899
OV_5678	Herpes simplex virus	HSV-R8306	DNA	Herpesviridae	Deletion mutant for Gamma 34.5 gene and addition of IL-10 gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	C57BL/6 mice xenograft for GL-261 (1.0E+5)	1.0E+6 pfu	NA	Increase in survival of mice up to 26 day	Intratumoral	NA	NA	NA	US7744899